Pharmacology Notes: Cardiotonics, Antihypertensives & Anti-Anginals
Comprehensive Pharmacy Semester 5 notes covering:
- Heparin mechanisms
- Cardiotonics & Digitalis pharmacology
- Antihypertensive classifications
- Anti-anginal agents
Download PDF notes, PPT slides, and study materials for Pharmacology 2
Keywords:
- Cardiac Glycosides Pharmacology PDF
- ACE Inhibitors Notes Download
- Antihypertensive Drug Classification
- Nitroglycerine Mechanism PPT
- Pharmacy Semester 5 Study Material
Comprehensive Pharmacology Notes
Cardiotonics & Digitalis
Definition: Cardiotonics are drugs that increase myocardial contractility
Digitalis Pharmacology:
- Inhibits Na+/K+ ATPase → ↑ intracellular Ca²+
- Positive inotropic effect
- Toxicity: Arrhythmias, visual disturbances
Antihypertensive Agents
Classifications:
- ACE Inhibitors (Enalapril)
- ARBs (Losartan)
- β-blockers (Atenolol)
- Ca²+ Channel Blockers
Centrally Acting Agents:
Clonidine:
- α₂ agonist → ↓ sympathetic outflow
- ADRs: Dry mouth, sedation
Anti-Anginal Drugs
Nitroglycerine Mechanism:
- Converts to NO → Vasodilation
- ↓ Preload and afterload
- Sublingual administration
Heparin Pharmacology
- Antithrombin III activation
- Monitoring via aPTT
- Antidote: Protamine sulfate
Potassium Channel Activators
- Minoxidil: Opens K+ channels → Vasodilation
- Used in resistant hypertension
Info!
If you are the copyright owner of this document and want to report it, please visit the copyright infringement notice page to submit a report.
