Capsule PDF: Handwritten Notes
Definition: “Capsules are unit solid dosage forms in which a drug is enclosed within a soluble shell of gelatin or similar material intended to be swallowed whole.”
According to B.P, “Capsules are solid preparations with hard or soft shells of various shapes and capacities, usually containing a single dose of active ingredients.”
Advantages: (over tablet) - Tasteless and odourless, so used to mask unpleasant taste and odour of drugs - Attractive appearance - Easy to administer - Economical - Easy to handle and carry - Protect drug from damage due to humidity and light - Liquid substances can be filled
Disadvantages: - Not suitable for hygroscopic and deliquescent substances as they absorb moisture present in shell and shell become brittle - Less stable as compared to tablet - Some of the tablets are divided into halves and quarters by drawing lines during manufacturing to facilitate breakage whenever a fractional dose is required - The incompatibility of medicaments and their deterioration due to environmental factors are less in tablet
Classification: [The classification would go here]
Subject: Industrial pharmacy 1 Semester: Sixth sem, sem 6 Course: Bachelor of Pharmacy, BPharm
Detailed Explanation
Capsules are a popular dosage form in the pharmaceutical industry, known for their ease of administration and ability to mask the unpleasant taste and odour of drugs. They provide an attractive appearance and are economical to produce. Capsules are easy to handle and carry, and they protect the drug from damage due to humidity and light. Liquid substances can also be filled into capsules, providing versatility in drug formulation.
However, capsules have some disadvantages. They are not suitable for hygroscopic and deliquescent substances as these substances absorb moisture present in the shell, causing the shell to become brittle. Capsules are also less stable compared to tablets, and some tablets are divided into halves and quarters by drawing lines during manufacturing to facilitate breakage whenever a fractional dose is required. The incompatibility of medicaments and their deterioration due to environmental factors are less in tablets.
Understanding the advantages and disadvantages of capsules is crucial for developing effective pharmaceutical formulations. This document provides a comprehensive overview of capsule formulation, highlighting the key factors to consider in the development and manufacturing of high-quality capsule products.
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