Capsule Manufacturing Defects: Handwritten Notes
Handwritten notes pdf: 1) Lumpy or mis-shaped capsule 2) Improper rectification 3) Failure to separate 4) Dented capsule 5) Telescopic 6) Popping 7) Brittleness 8) Other defects
Subject: Industrial Pharmacy 1 Semester: Sixth sem, sem 6 Course: Bachelor of Pharmacy, BPharm
Detailed Explanation
Capsule manufacturing defects are a significant concern in the pharmaceutical industry. This document provides a detailed overview of common defects encountered during capsule production. Understanding these defects is crucial for ensuring the quality and efficacy of the final product.
1) **Lumpy or mis-shaped capsule:** This defect occurs due to improper mixing or handling of the capsule formulation, resulting in unevenly shaped capsules. 2) **Improper rectification:** This defect happens when capsules are not correctly oriented or filled during the production process. 3) **Failure to separate:** This issue arises when capsules stick together, preventing them from being adequately separated during packaging. 4) **Dented capsule:** Capsules may become dented due to mechanical handling or pressure during the manufacturing process. 5) **Telescopic:** This defect occurs when one part of the capsule slides into another, causing a telescoping effect. 6) **Popping:** Popping defects are caused by excessive pressure during filling, leading to the capsule's top or bottom popping out. 7) **Brittleness:** Capsules may become brittle and prone to breaking due to improper storage conditions or exposure to moisture. 8) **Other defects:** Various other defects can occur during capsule manufacturing, such as cracking, splitting, or color variations.
By understanding and addressing these common defects, pharmaceutical professionals can improve the quality and consistency of capsule products, ensuring they meet regulatory standards and provide effective treatments for patients.
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