Autocoids and Related Drugs: Hand Written Notes
Complete pharmacology notes on autocoids and related medications in PDF format. Includes:
- Classification of autocoids
- Histamine and antihistamines
- Serotonin agonists/antagonists
- Eicosanoids and their modulators
- Clinical applications and drug actions
Keywords: autocoids PDF notes, histamine pharmacology, serotonin drugs study material, eicosanoids PPT download, medicinal chemistry notes
Comprehensive Guide to Autocoids and Related Drugs
Autocoids are locally acting endogenous substances that function as chemical messengers. These handwritten notes provide detailed insights into their pharmacology and therapeutic applications.
Major Autocoid Classes
- Biogenic Amines:
- Histamine and antihistamines
- Serotonin (5-HT) and its modulators
- Eicosanoids:
- Prostaglandins
- Leukotrienes
- Thromboxanes
- Peptide Autocoids:
- Bradykinin
- Angiotensin
Key Drug Categories
- Histamine Receptor Antagonists:
- H1 blockers (Loratadine, Cetirizine)
- H2 blockers (Ranitidine, Famotidine)
- Serotonin Modulators:
- 5-HT1 agonists (Sumatriptan)
- 5-HT3 antagonists (Ondansetron)
- Eicosanoid Inhibitors:
- COX inhibitors (Aspirin, Celecoxib)
- Leukotriene antagonists (Montelukast)
Clinical Applications
- Allergy management (Antihistamines)
- Migraine treatment (Triptans)
- Inflammation control (NSAIDs)
- Peptic ulcer therapy (H2 blockers)
Mechanisms of Action
- Histamine receptor competitive antagonism
- Serotonin reuptake inhibition
- Cyclooxygenase enzyme inhibition
- Leukotriene synthesis blockade
Recent Advances
- New-generation antihistamines
- Targeted monoclonal antibody therapies
- Dual COX/LOX inhibitors
- Neurokinin receptor antagonists
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