Tablet (Industrial Pharmacy 1): Handwritten Notes
Tablets: a. Introduction, ideal characteristics of tablets, classification of tablets. Excipients, formulation of tablets, granulation methods, compression and processing problems. Equipments and tablet tooling. b. Tablet coating: Types of coating, coating materials, formulation of coating composition, methods of coating, equipment employed and defects in coating. c. Quality control tests: In-process and finished product tests.
Detailed Explanation
Tablets are one of the most common dosage forms in the pharmaceutical industry. This document provides a comprehensive overview of tablet formulation, manufacturing processes, and quality control tests. The introduction covers the ideal characteristics of tablets and their classification, highlighting the importance of excipients in the formulation process.
Granulation methods are discussed in detail, including wet granulation, dry granulation, and direct compression. The document also addresses common compression and processing problems, as well as the equipment and tablet tooling used in the manufacturing process.
Tablet coating is another essential aspect covered in this document. Various types of coating, such as sugar coating, film coating, and enteric coating, are explained, along with the materials and methods used in the coating process. The document also identifies common defects in tablet coating and provides insights into troubleshooting these issues.
Quality control tests are critical to ensuring the safety and efficacy of the final product. This section outlines the in-process and finished product tests performed on tablets, including weight variation, hardness, friability, disintegration, and dissolution tests.
Overall, this document serves as a valuable resource for students and professionals in the pharmaceutical industry, providing essential knowledge for the development and manufacturing of high-quality tablets.
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