Metabolic pathway (Cognosy 2):- Hand Written Notes

Metabolic Pathways Notes - B.Pharm Sem 5 Pharmacognosy 2

Download PDF Notes covering essential metabolic pathways:

  • Shikimic acid pathway
  • Mevalonic acid pathway
  • Acetate-malonate pathway
  • Biosynthesis of secondary metabolites

Keywords: Metabolic pathway PDF, Pharmacognosy notes download, B.Pharm sem 5 PPT, Biosynthesis pathways, Medicinal plant biochemistry

Comprehensive Guide to Metabolic Pathways in Pharmacognosy

1. Major Metabolic Pathways

  • Shikimic Acid Pathway:
    • Production of aromatic amino acids
    • Source of phenolic compounds
    • Important for tannins and lignins
  • Acetate-Malonate Pathway:
    • Fatty acid biosynthesis
    • Polyketide formation
    • Anthraquinones production

2. Clinical Significance

PathwayMedicinal Compounds
MevalonateSteroids, Terpenoids
ShikimateAlkaloids, Flavonoids
AcetateProstaglandins, Antibiotics

3. Key Enzymes & Reactions

  1. HMG-CoA reductase in cholesterol synthesis
  2. PAL enzyme in phenylpropanoid pathway
  3. Polyketide synthase in antibiotic production

4. Pathway Interrelationships

  • Cross-talk between primary and secondary metabolism
  • Regulation through feedback inhibition
  • Compartmentalization in plant cells

5. Study Resources

This 90-page guide includes:

  • Detailed pathway diagrams
  • Enzyme mechanism illustrations
  • Case studies of drug biosynthesis
  • Pharmaceutical applications chart

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