Metabolic Pathways Notes - B.Pharm Sem 5 Pharmacognosy 2
Download PDF Notes covering essential metabolic pathways:
- Shikimic acid pathway
- Mevalonic acid pathway
- Acetate-malonate pathway
- Biosynthesis of secondary metabolites
Keywords: Metabolic pathway PDF, Pharmacognosy notes download, B.Pharm sem 5 PPT, Biosynthesis pathways, Medicinal plant biochemistry
Comprehensive Guide to Metabolic Pathways in Pharmacognosy
1. Major Metabolic Pathways
- Shikimic Acid Pathway:
- Production of aromatic amino acids
- Source of phenolic compounds
- Important for tannins and lignins
- Acetate-Malonate Pathway:
- Fatty acid biosynthesis
- Polyketide formation
- Anthraquinones production
2. Clinical Significance
| Pathway | Medicinal Compounds |
|---|---|
| Mevalonate | Steroids, Terpenoids |
| Shikimate | Alkaloids, Flavonoids |
| Acetate | Prostaglandins, Antibiotics |
3. Key Enzymes & Reactions
- HMG-CoA reductase in cholesterol synthesis
- PAL enzyme in phenylpropanoid pathway
- Polyketide synthase in antibiotic production
4. Pathway Interrelationships
- Cross-talk between primary and secondary metabolism
- Regulation through feedback inhibition
- Compartmentalization in plant cells
5. Study Resources
This 90-page guide includes:
- Detailed pathway diagrams
- Enzyme mechanism illustrations
- Case studies of drug biosynthesis
- Pharmaceutical applications chart
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