Anti-anginal: Medicinal Chemistry 2: Unit 2 || Handwritten Notes
Download detailed handwritten notes on Anti-anginal Agents, covering topics such as Vasodilators, Calcium Channel Blockers, Diuretics, and Anti-hypertensive Agents. These notes are essential for students studying pharmaceutical chemistry and preparing for exams.
Keywords: download PDF, handwritten notes, anti-anginal agents, vasodilators, calcium channel blockers, diuretics, anti-hypertensive agents, pharmaceutical chemistry.
Anti-anginal: Medicinal Chemistry 2: Unit 2 – A Comprehensive Guide
Medicinal Chemistry 2: Unit 2 focuses on the study of Anti-anginal Agents, including Vasodilators, Calcium Channel Blockers, Diuretics, and Anti-hypertensive Agents. This unit is a critical part of the pharmaceutical chemistry curriculum, providing students with an in-depth understanding of the chemical structures, mechanisms of action, and therapeutic applications of these drugs.
Vasodilators
Vasodilators are drugs that relax the smooth muscles in blood vessels, leading to vasodilation and reduced blood pressure. Examples include:
- Amyl nitrite
- Nitroglycerin*
- Pentaerythritol tetranitrate
- Isosorbide dinitrite*
- Dipyridamole
Calcium Channel Blockers
Calcium channel blockers inhibit the influx of calcium ions into cardiac and smooth muscle cells, leading to vasodilation and reduced cardiac workload. Examples include:
- Verapamil
- Bepridil hydrochloride
- Diltiazem hydrochloride
- Nifedipine
- Amlodipine
- Felodipine
- Nicardipine
- Nimodipine
Diuretics
Diuretics are drugs that promote the excretion of water and electrolytes through urine. They are classified into:
- Carbonic anhydrase inhibitors: Acetazolamide*, Methazolamide, Dichlorphenamide
- Thiazides: Chlorthiazide*, Hydrochlorothiazide, Hydroflumethiazide, Cyclothiazide
- Loop diuretics: Furosemide*, Bumetanide, Ethacrynic acid
- Potassium-sparing diuretics: Spironolactone, Triamterene, Amiloride
- Osmotic diuretics: Mannitol
Anti-hypertensive Agents
Anti-hypertensive agents are used to treat high blood pressure and include:
- Timolol
- Captopril
- Lisinopril
- Enalapril
- Benazepril hydrochloride
- Quinapril hydrochloride
- Methyldopate hydrochloride*
- Clonidine hydrochloride
- Guanethidine monosulphate
- Guanabenz acetate
- Sodium nitroprusside
- Diazoxide
- Minoxidil
- Reserpine
- Hydralazine hydrochloride
These handwritten notes provide a detailed explanation of the chemical structures, mechanisms of action, and therapeutic uses of these drugs, making them an invaluable resource for students and professionals in the field of pharmaceutical chemistry.
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