Antibiotics Unit:- 3 (Med Chem:- 3):- Hand Written Notes

Anti-tubercular Agents: Download PDF and PPT

This document focuses on anti-tubercular agents, urinary tract anti-infective agents, and antiviral drugs. It provides an in-depth exploration of synthetic anti-tubercular agents, anti-tubercular antibiotics, and their mechanism of action. Additionally, it covers the SAR (Structure-Activity Relationship) of quinolones and the pharmacological profiles of antiviral agents.

  • Synthetic anti-tubercular agents: Isoniazid, Ethionamide, Ethambutol, Pyrazinamide
  • Anti-tubercular antibiotics: Rifampicin, Rifabutin, Cycloserine
  • Urinary tract anti-infective agents: Quinolones, Furazolidine, Nitrofurantoin
  • Antiviral agents: Acyclovir, Zidovudine, Lamivudine, Saquinavir

Detailed Explanation

The document explores the field of anti-tubercular agents, offering a detailed analysis of both synthetic compounds and antibiotics. Synthetic agents such as Isoniazid and Ethambutol are covered, focusing on their therapeutic roles in combating Mycobacterium tuberculosis. Anti-tubercular antibiotics like Rifampicin and Cycloserine are analyzed for their broad-spectrum activity and clinical significance.

The urinary tract anti-infective agents section delves into the SAR of quinolones, including well-known drugs like Ciprofloxacin and Moxifloxacin. These agents are highlighted for their efficacy in treating urinary and systemic infections. Additionally, miscellaneous compounds like Nitrofurantoin and Methenamine are discussed for their specialized roles.

Antiviral agents are a key focus, with coverage of various classes and mechanisms. Drugs like Acyclovir, Zidovudine, and Saquinavir are highlighted for their effectiveness in managing viral infections such as herpes and HIV. The document also touches upon newer agents, detailing their mechanisms of action and therapeutic potential.

This comprehensive guide is essential for understanding the pharmacological and clinical relevance of these important drug classes. Download the PDF and PPT for a deeper dive into the subject.

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