Anti Anginal Drugs:- PPT / PDF
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Comprehensive Guide to Anti-Anginal Drugs
Anti-anginal drugs are a crucial class of medications used in the management of angina pectoris, a symptom of coronary artery disease characterized by chest pain due to reduced blood flow to the heart muscle. This comprehensive guide explores various aspects of anti-anginal medications, their mechanisms of action, and clinical applications.
Types of Anti-Anginal Drugs
1. Nitrates: The most commonly prescribed anti-anginals, including nitroglycerin and isosorbide dinitrate. They work by vasodilation, reducing cardiac preload and oxygen demand.
2. Beta Blockers: Such as metoprolol and atenolol, decrease heart rate and contractility, reducing myocardial oxygen consumption.
3. Calcium Channel Blockers: Including amlodipine and diltiazem, promote coronary vasodilation and reduce afterload.
4. Potassium Channel Openers: Like nicorandil, combine nitrate-like and potassium channel opening actions.
Mechanisms of Action
Anti-anginal drugs primarily work through three main mechanisms:
- Reducing myocardial oxygen demand
- Increasing coronary blood flow
- Improving oxygen delivery to the heart
Clinical Considerations
When prescribing anti-anginal therapy, clinicians must consider:
- Patient's comorbidities
- Frequency and severity of angina attacks
- Potential drug interactions
- Long-term management strategies
Download our complete PPT and PDF package to access detailed information on dosage regimens, adverse effects, and recent advances in anti-anginal therapy.
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